About Behçet’s Disease

Behçet’s disease is an autoimmune disorder related to inflammation in the blood vessels. It is characterized by mouth sores, genital sores, inflammation in certain parts of the eye (uveitis) and arthritis. In extreme cases, the symptoms include inflammation of the brain and spinal cord, and inflammation of the digestive system.

Behçet’s Disease Care at Children’s Wisconsin

The most common treatments for Behçet’s disease include corticosteroids, to reduce pain and inflammation, and immunosuppressive drugs, to help keep the body from attacking itself.

Henoch-Schönlein Purpura (HSP) is a common type of vasculitis, a condition that causes blood vessels to become inflamed. It is most often seen in children between the ages of 5 and 15 and is more common in boys. The exact cause of HSP is currently unknown.

Symptoms and Treatment

Symptoms can vary for each child, but the most common signs of HSP include:

• Purpura: A rash caused by bleeding under the skin.
• Joint pain and swelling.
• Abdominal pain and bleeding in the digestive tract.
• Nephritis: Inflammation of the kidneys.
• Subcutaneous edema: Swelling just below the skin.
• In rare cases, inflammation of the testicles or a brain dysfunction may occur.

Since symptoms can mimic other medical problems, it's crucial to consult a doctor for a proper diagnosis.

Treatment for HSP is determined by a doctor based on the child's specific condition and which organs are affected. The main goals are to manage the symptoms and ensure the child is comfortable. Treatment may include:

• Maintaining good hydration and nutrition.
• Using medications like acetaminophen for pain.
• Taking glucocorticoids to help control inflammation.
• Regularly monitoring urine and blood pressure to check for kidney issues.

About Pediatric Vasculitis

Vasculitis is a term that refers to a number of different rheumatic conditions, all of which involve inflammation and/or damage to the blood vessels. Vasculitis can be acute and self limiting or chronic and involve many organs. The most common form of vasculitis in children is Henoch-Schönlein purpura (HSP) which affects blood vessels in the skin, intestines and often the kidneys. The second most common type of pediatric vasculitis is Kawasaki disease which affects the arteries. While we don’t yet know what causes vasculitis, research suggests that autoimmune disease and infections agents may be involved. 

Pediatric Vasculitis Care at Children’s Wisconsin

Our goal is to diagnose your child’s vasculitis early and partner with you to achieve remission. For some milder forms of vasculitis, your child may only need time, rest and over-the-counter anti-inflammatory drugs. If your child’s condition is more severe or complicated, we may recommend prescription oral medications, and/or IV medications.

About Scleroderma

Scleroderma is a skin disease marked by hardening patches on your child’s skin. He or she may also have stiff hands or feel especially sensitive to cold and heat in his or her hands and feet. In most children, scleroderma is localized, meaning it only affects the skin. This form is called localized scleroderma or morphea. In very rare instances, children can develop systemic scleroderma, which affects skin elasticity, internal organs and joint movement.

Scleroderma Care at Children’s Wisconsin

As scleroderma’s effects can vary widely, we design a treatment approach at Children’s Wisconsin that is specific to your child’s needs. We focus on managing symptoms and bringing you and your child relief. Our approach may include medication, therapy and treating the skin condition locally.