Rene Andrade-Machado, MD

• Mequon Clinic-Children's Wisconsin
  1655 W. Mequon Road
  Mequon, WI 53092
  Appointment Phone: (414) 607-5280
  
• Milwaukee Campus-Children's Wisconsin
  8915 W. Connell Court
  Milwaukee, WI 53226
  Appointment Phone: (414) 266-3464
  

Services

• Neurology
• Neuroscience

I enjoy and it is my primary goal offering, patient-orientated, companionate, comprehensive and holistic medical management of patients with epilepsy and its comorbidities. I am committed to improve quality of life, not only of the patients with epilepsy but also, the quality of life of their family. My enthusiasm, optimism and empathy are the source of all the solution I can find tailored to the medical problem of each of my patient.

Certifications

• Neurophysiology

Areas of Interest

• Epilepsy
• Epilepsy surgery
• Tuberous Sclerosis Complex
• Genetic syndromes
• Neuropsychology

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Education

• 1995, Superior Health Science Institute , Villa Clara, MD

Residencies

• 2015, National Institute of Colombia - Neurology residency
• 1999, National Neurology and Neurosurgery Institute - Neurology residency

Fellowships

• 2020, Children hospital of Michigan - Pediatric Epilepsy Fellowship
• 2021, Detroit Medical Center - Neurophysiology

Awards

Research

Suicidal risk and suicide attempts in people treated with antiepileptic drugs for epilepsy.
Machado RA, Espinosa AG, Melendrez D, González YR, García VF, Rodríguez YQ.Seizure. 2011 May;20(4):280-4. doi: 10.1016/j.seizure.2010.12.010. Epub 2011 Jan 26.PMID: 21269844
 
Periictal sign of the cross or Signum Crucis as a lateralizing sign in focal epilepsies: Not only a right temporal lobe epilepsy feature.
Arango-Jaramillo E, Lozano-García L, Benjumea-Cuartas V, Andrade-Machado R. Epilepsy Behav. 2018 Jan;78:52-56. doi: 10.1016/j.yebeh.2017.09.029. Epub 2017 Nov 22.PMID: 29175220

Efficacy and tolerability of add-on Lacosamide treatment in adults with Lennox-Gastaut syndrome: An observational study.
Andrade-Machado R, Luque-Navarro-de Los Reyes J, Benjumea-Cuartas V, Restrepo JF, Jaramillo-Jiménez E, Andrade-Gutierrez G, Espinosa AG.Seizure. 2015 Dec;33:81-7. doi: 10.1016/j.seizure.2015.10.009. Epub 2015 Oct 25.PMID: 26606192
 
Cholesterol concentrations and clinical response to sertraline in patients with epilepsy: preliminary results.
 
Efficacy and tolerability of lamotrigine in juvenile myoclonic epilepsy in adults: a prospective, unblinded randomized controlled trial.
Machado RA, García VF, Astencio AG, Cuartas VB.Seizure. 2013 Dec;22(10):846-55. doi: 10.1016/j.seizure.2013.07.006. Epub 2013 Aug 1.PMID: 23916525 Clinical Trial.
 
Wisconsin Card Sorting Test performance and impulsivity in patients with temporal lobe epilepsy: suicidal risk and suicide attempts.
Garcia Espinosa A, Andrade Machado R, Borges González S, García González ME, Pérez Montoto A, Toledo Sotomayor G.Epilepsy Behav. 2010 Jan;17(1):39-45. doi: 10.1016/j.yebeh.2009.09.010. Epub 2009 Nov 13.PMID: 19914140
 
Incorporating patients' perceptions of their health into clinical decision-making processes.
Machado RA.J Neurosci Rural Pract. 2014 Nov;5(Suppl 1):S5-6. doi: 10.4103/0976-3147.145192.PMID: 25540540 

Ictal extension (dorsiflexion) of the toes in a patient with temporal lobe epilepsy: a new ictal lateralizing sign.
Machado RA, Mila RA.Epilepsy Behav. 2010 Aug;18(4):481-4. doi: 10.1016/j.yebeh.2010.05.011. Epub 2010 Jun 30.PMID: 20580621

Reelin, tau phosphorylation and psychiatric complications in patients with hippocampal sclerosis and structural abnormalities in temporal lobe epilepsy.
Machado RA, Benjumea-Cuartas V, Zapata Berruecos JF, Agudelo-Flóres PM, Salazar-Peláez LM.Epilepsy Behav. 2019 Jul;96:192-199. doi: 10.1016/j.yebeh.2019.04.052. Epub 2019 May 29.PMID: 31150999 Review.
 
Temporal plus epilepsy: Anatomo-electroclinical subtypes.
Andrade-Machado R, Benjumea-Cuartas V.Iran J Neurol. 2016 Jul 6;15(3):153-63.PMID: 27648177 
.
The role of ketamine-induced beta activity in the treatment of refractory status epilepticus. Is the EEG useful to determine responder's rate? A retrospective study.
Machado RA, Patel J, Elsayed MS.Epilepsy Behav. 2022 Feb;127:108512. doi: 10.1016/j.yebeh.2021.108512. Epub 2021 Dec 30.PMID: 34974373
 
Benign epilepsy with centro temporal spikes: Is there a thalamocortical network dysfunction present? Adding supporting evidence from SPECT imaging.
Andrade-Machado R.Seizure. 2020 Aug;80:143-144. doi: 10.1016/j.seizure.2020.06.023. Epub 2020 Jun 16.PMID: 32570171 

Lacosamide in Lennox-Gastaut syndrome: case report.
Andrade-Machado R, Benjumea-Cuartas V, Jaramillo-Jimenez E.Clin Neuropharmacol. 2012 May-Jun;35(3):148-9. doi: 10.1097/WNF.0b013e318255b649.PMID: 22592511

Early thalamic lesions in patients with sleep-potentiated epileptiform activity.
Andrade-Machado R.Neurology. 2012 Nov 27;79(22):2218; author reply 2218-9. doi: 10.1212/01.wnl.0000423466.65431.4a.PMID: 23183283 No abstract available.

Mortality in patients with refractory temporal lobe epilepsy at a tertiary center in Cuba.
Andrade-Machado R, Benjumea-Cuartas V, Santos-Santos A, Sosa-Dubón MA, García-Espinosa A, Andrade-Gutierrez G.Epilepsy Behav. 2015 Dec;53:154-60. doi: 10.1016/j.yebeh.2015.08.038. Epub 2015 Nov 12.PMID: 26575257

Suicidal risk, affective dysphoric disorders, and quality-of-life perception in patients with focal refractory epilepsy. Andrade-Machado R, Ochoa-Urrea M, Garcia-Espinosa A, Benjumea-Cuartas V, Santos-Santos A.Epilepsy Behav. 2015 Apr;45:254-60. doi: 10.1016/j.yebeh.2015.01.005. Epub 2015 Mar 29.PMID: 25825368
 
Gelastic seizures involving the left parietal lobe.
Machado RA, Astencio AG.Epilepsy Behav. 2012 Jan;23(1):87-9. doi: 10.1016/j.yebeh.2011.11.009. Epub 2011 Dec 23.PMID: 22197123

Recognition of interictal and ictal discharges on EEG. Focal vs generalized epilepsy.
Andrade-Machado R, Benjumea Cuartas V, Muhammad IK.Epilepsy Behav. 2021 Apr;117:107830. doi: 10.1016/j.yebeh.2021.107830. Epub 2021 Feb 25.PMID: 33639439 Review.
 
Temporal plus epilepsy: Anatomo-electroclinical subtypes.
Andrade-Machado R, Benjumea-Cuartas V.Iran J Neurol. 2016 Jul 6;15(3):153-63.PMID: 27648177 

Should be prescribed lacosamide in patients with Lennox-Gastaut syndrome?
Andrade-Machado R.Acta Neurol Scand. 2014 Aug;130(2):e35-6. doi: 10.1111/ane.12251.PMID: 25052286 
 
Benign epilepsy with centro temporal spikes: Is there a thalamocortical network dysfunction present? Adding supporting evidence from SPECT imaging.
Andrade-Machado R.Seizure. 2020 Aug;80:143-144. doi: 10.1016/j.seizure.2020.06.023. Epub 2020 Jun 16.PMID: 32570171 
 
Lacosamide in Lennox-Gastaut syndrome: case report.
Andrade-Machado R, Benjumea-Cuartas V, Jaramillo-Jimenez E.Clin Neuropharmacol. 2012 May-Jun;35(3):148-9. doi: 10.1097/WNF.0b013e318255b649.PMID: 22592511
 
Early thalamic lesions in patients with sleep-potentiated epileptiform activity.
Andrade-Machado R.Neurology. 2012 Nov 27;79(22):2218; author reply 2218-9. doi: 10.1212/01.wnl.0000423466.65431.4a.PMID: 23183283

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