Cyclophosphamide in nephrotic syndrome (1080)

Key points below


Reason for prescribing

Cyclophosphamide is used to treat different types of kidney disease.  It can be used along with other medicines, like Prednisone®, to treat these diseases. It comes as a tablet or may be given through a vein.  Brand names include Cytoxan.

How and when to give the medicine

Your child’s doctor or nurse will explain how and when to give this medicine to your child.  If you have questions, ask the doctor, nurse, or pharmacist.

Special advice for giving this medicine with food

Possible side effects

The following is a list of some of the possible side effects of this medicine.  If your child has these or other side effects, tell the doctor, nurse, or pharmacist.

Possible side effects

Uncommon side effects

When given through a vein, nausea and vomiting may occur 6 to 8 hours after getting this medicine and could last 8 to 24 hours.

Special information

General information:

Storage, refills and when to throw away:  



Call your child’s doctor, nurse, or clinic if you have any questions or concerns or if your child:

  • Has a hard time breathing or is short of breath.
  • Has a fever of 101.2° F (38.5° C) or higher for more than two days, or if the fever is not relieved by over-the-counter fever reducer medicine.
  • Has any pain when urinating or if you think your child’s urine has blood in it.
  • Has been exposed to chicken pox or the measles.
  • Is vomiting and is not able to keep the medicine in their stomach.
  • Had a white blood cell count checked at another hospital or clinic and it is below 3,000.
  • Has special health care needs that were not covered by this information.