Hydroxyurea for sickle cell disease (1564)

Key points below

What is hydroxyurea? 

It is a medicine to treat sickle cell disease.  It raises levels of baby (fetal) hemoglobin and lowers the amount of sickle (S) hemoglobin.

If your child takes this medicine, they will be seen in the clinic and have blood counts checked every 2 to 3 months.  Your child may need to get extra blood drawn more often at certain times during their treatment.

Why is it used?

What side effects should I watch for?

If you have any side effects, talk with the sickle cell doctor. The doctor may have you stop taking the medicine for a short time.  Most side effects get better when the medicine is stopped for a week or two. The medicine should not be stopped unless the doctor says it is ok to do so.

Important note for females:

For other health and wellness information, check out this resource: https://kidshealth.org/ChildrensWi/en/parents



Call the sickle cell clinic if you have any questions or concerns listed below or if your child has special health care needs not covered by this information.

  • Is more tired than normal.
  • Has problems after starting Hydroxyurea.
  • Has special health care needs not covered by this information. 

Monday through Friday (8:00 am to 4:30 pm) 

Sickle Cell Clinic: 414-266-2420.  Ask to talk with a nurse.

After hours, weekends, or holidays

Call 414-266-2420.  You will be transferred to the operator if your call is urgent.  Ask for the hematologist on call to be paged.