Transposition of the great arteries (TGA or d-TGA) is a serious heart defect that is present at birth (congenital). It occurs when the fetal heart doesn’t develop properly during the first two months of pregnancy. In TGA, two main arteries of the heart are reversed.
Normally, the aorta is connected to the left ventricle (the lower left chamber of the heart). It pumps oxygen-rich (red) blood to the body. The pulmonary artery is connected to the right ventricle (the lower right chamber of the heart). It pumps oxygen-poor (blue) blood to the lungs.
In babies with TGA, it’s the opposite. The aorta is connected to the right ventricle and the pulmonary artery is connected to the left ventricle. The result is oxygen-rich blood being sent to the lungs and oxygen-poor blood sent to the body. This can be fatal.
Other issues caused by TGA include:
- The right ventricle is not strong enough to pump blood to the body. As a result, it can be damaged from the stress.
- The left ventricle may pump more blood into the lung than needed. This can lead to a strain in the blood vessels in the lungs.