Qizhen Shi,

  • Investigator, Children's Research Institute
  • Associate professor, Medical College of Wisconsin




  • Hematology, Oncology and Transplant

Research interests

  • Bleeding and blood disorders
  • Hemophilia

Study interests

  • Hemophilia
  • The association between von Willebrand factor and factor FVIII
  • Gene therapy
  • Hematopoietic stem cells
  • Immune response in gene therapy


  • Medical degree, Fujian Medical University, China, 1990
  • MS, Hematology, Fujian Medical University, Fuzhou, Fujian, China, 1993
  • Doctorate, Hematology, Fujian Medical University, Fuzhou, Fujian, China, 1998
  • Resident in Internal Medicine, Fujian Institute of Hematology, Fujian Medical University Union Hospital, Fujian, China, 1995
  • Postdoctoral fellow, Medical College of Wisconsin, Pediatric Oncology, 2001
  • Postdoctoral Fellow, Medical College of Wisconsin, Pediatric Hemtology Blood Research Institute, Milwaukee, Wisconsin, 2006


  • Chinese Medical License (Registration no: 210020. China)

Education and Awards



  • The Leader of Fujian Provincial Academic and Technology, 1998; Outstanding New Investigator Award, American Society of Gene and Cell Therapy, 2011; Martin Villar Haemostasis Award, 2013
  • Symposium HOT Topic Presenter, the Scientific and Standardization Committee of International Society for Thrombosis and Haemostasis, 2012
  • Member, American Society of Hematology, International Society on Thrombosis and Haemostasis, American Heart Association - Scientific Council; Abstract reviewer for the 54th American Society of Hematology Annual Meeting, 2012
  • Ad Hoc Reviewer for Blood, Journal of Thrombosis and Haemostasis, Current Gene Therapy, Drug Design, Development and Therapy, Molecular Pharmaceutics, Journal of Genetic Syndromes & Gene Therapy
  • Ad Hoc Reviewer for the Natural Sciences and Engineering Research Council of Canada for Collaborative Health Research Projects and the Trust/DBT India Alliance Intermediate Fellowship for Biomedical Research Fellowship Program, and National Nature Science Foundation of China

Research and publications


  • Platelet-Derived FVIII Gene Therapy of Hemophilia A, National Institutes of Health/NHLBI RO1, principal investigator
  • Platelet Gene Therapy for Hemophilia, MACC Fund, principal investigator
  • “The impact of VWF on FVIII immune response in hemophilia A with inhibitors”, Biotest Research grant, principal investigator
  • “Function of induced regulatory T cells in platelet gene therapy”, CRI PIR grant, principal investigator