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Clinical trials
- Participate in a clinical trial
- For medical professionals
- Active clinical trials for pediatric cancers
- CAR-20/19-T cells in pediatric and young adult patients with relapsed/refractory B Cell Acute Lymphoblastic Leukemia (CAR-20/19-T) phase 1 clinical trial
- Unrelated and partially matched related donor peripheral stem cell transplantation for patients with hematologic malignancies clinical trial
- Early stage research
Active clinical trials
Cancer Clinical Trials - NYMC-600
Protocol Summary
- Protocol No
- NYMC-600
- Principal Investigator
- Nicole Liberio
- Phase
- II
- Title
- A Phase II Intrapatient Open-Label Dose Escalation Trial of Defibrotide in Hematopoietic Cell Transplantation (HCT) Recipients with Sinusoidal Obstructive Syndrome (SOS) Post-HCT Associated with Either Renal and/or Pulmonary Dysfunction with Either Refractory or Progressive Disease Following Defibrotide Therapy
- Associated Disease(s)
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Bone Marrow Transplant and Cellular Therapy
- Description (Summary)
- This project is being done to determine the safety and tolerability of increasing doses of defibrotide within a single patient with SOS/VOS disease after hematopoietic cell transplantation associated with either kidney and/or lung impairment that has not obtained a complete response or progressed in severity with standard doses of defibrotide.
- Participating Institutions
- Childrens Hospital of Wisconsin
- ClinicalTrials.gov
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