Active clinical trials

Clinical Trials - Diseases by specialty group


Leukemia 11


    A Phase 3 Randomized Trial for Patients with De Novo AML Comparing Standard Therapy Including Gemtuzumab Ozogamicin (GO) to CPX-351 with GO, and the Addition of the FLT3 Inhibitor Gilteritinib for Patients with FLT3 Mutations

    A Phase I Study of Venetoclax to Augment Epigenetic Modification and Chemotherapy in Pediatric and Young Adult Patients with Relapsed and Refractory Acute Myeloid Leukemia

    IIT-MOSKOP-MABD
  • Acute Lymphoblastic Leukemia (ALL)
  • Acute Myelogenous Leukemia (AML)
  • Chronic Mylegenous Leukemia (CML)
  • Myeloma/Myelodysplastic Syndrome (MDS)
  • Other Leukemia
    Matched Unrelated Donor and Partially Matched Related Donor Peripheral Stem Cell Transplantation with Alpha/Beta T-Cell and B-Cell Depletion for Patients with Hematologic Malignancies with Targeted ATG Dosing Pilot Study, IDE 13641

    IIT-Steineck-CARTPLUS: Chimeric Antigen Receptor T-cell Pediatrics Living with Uncertainty (CAR T-PLUS) Intervention Proof of Concept Study

    MAGIC-LRPEDS
  • Acute Lymphoblastic Leukemia (ALL)
  • Acute Myelogenous Leukemia (AML)
  • Other Leukemia
    Serial Response and Biomarker-Guided Steroid Taper for Children with GVHD

    A Phase II Pilot Study of Donor-Derived Ex-Vivo Expanded Natural Killer Cell Infusions in Children and Young Adults with High-Risk Acute Myeloid Leukemia Receiving Myeloablative HLA-Haploidentical Hematopoietic Cell Transplant: A Multicenter Pediatric Transplantation and Cellular Therapy Consortium (PTCTC) Study (EXCEL Trial)

    TACL-T2020-006
  • Acute Lymphoblastic Leukemia (ALL)
  • Acute Myelogenous Leukemia (AML)
  • Myeloma/Myelodysplastic Syndrome (MDS)
  • Other Leukemia
    A Phase I Study of Tagraxofusp with or without Chemotherapy in Pediatric Patients with Relapsed or Refractory CD123 Expressing Hematologic Malignancies

    Evaluation of Long-term Safety in Paediatric Patients With B-precursor Acute Lymphoblastic Leukemia (ALL) who Have Been Treated With Either Blinatumomab or Chemotherapy, Followed by Transplantation

    COG-AALL1732
  • Acute Lymphoblastic Leukemia (ALL)
  • Other Leukemia
    A Phase 3 Randomized Trial of Inotuzumab Ozogamicin (NSC#: 772518) for Newly Diagnosed High-Risk B-ALL; Risk-Adapted Post-Induction Therapy for High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and Disseminated B-LLy

    COG-ACCL1931
  • Acute Lymphoblastic Leukemia (ALL)
  • Other Leukemia
    A Randomized Trial of Levocarnitine Prophylaxis to Prevent Asparaginase-Associated Hepatotoxicity in Adolescents and Young Adults Receiving Acute Lymphoblastic Leukemia Therapy

    Communication in the Early Pediatric Cancer Treatment Period

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Why participate in clinical trials?

Michael Burke, MD

"The steady improvement in survival for children with cancer is a direct result of their enrollment onto clinical trials; without which we would remain decades behind in terms of scientific advances in pediatric cancer." ~Michael J. Burke, MD