In this section
Clinical trials
- Participate in a clinical trial
- For medical professionals
- Active clinical trials for pediatric cancers
- CAR-20/19-T cells in pediatric and young adult patients with relapsed/refractory B Cell Acute Lymphoblastic Leukemia (CAR-20/19-T) phase 1 clinical trial
- Unrelated and partially matched related donor peripheral stem cell transplantation for patients with hematologic malignancies clinical trial
- Early stage research
Active clinical trials
Cancer Clinical Trials - NMDP-UMCC2018-081
Protocol Summary
- Protocol No
- NMDP-UMCC2018-081
- Principal Investigator
- Julie-An Talano
- Phase
- I/II
- Title
- A Phase 1/2 Multi-Center Trial of Vorinistat for Graft vs Host Disease Prevention in Children, Adolescents, and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation
- Associated Disease(s)
-
Bone Marrow Transplant and Cellular Therapy
- Description (Summary)
- The goal of Phase 1 studies is to find the dose that works best without causing severe side effects (often called the maximum tolerated dose, or MTD) and to identify the most common side effects. This is determined by giving subjects different doses of the investigational study intervention and carefully monitoring for side effects as well as how the body handles the investigational study intervention. The goal of Phase 2 studies is to test the safety and effectiveness of the investigational study treatment, i.e. does it work against your type of condition, and do the benefits outweigh the risks and side effects. This is usually done by comparing the outcomes of the subjects in the study to those of people who previously received standard treatment.
- Participating Institutions
- Childrens Hospital of Wisconsin
- ClinicalTrials.gov
Contact us
For more information about cancer and blood disorders clinical trials, email us or call
(414) 955-4727
Get a second opinion
It's important to know what your options are. We can provide expert opinions to verify or give more information about an initial diagnosis. Contact us today.
Why participate in clinical trials?
