Survivorship research

The Next Steps Team continues to provide the most current, evidence-based survivorship care for our patients. We are involved in national and international research groups, as well as our own local research efforts. The potential for long term complications, or late effects, after therapy is complete varies for each cancer survivor. Late effects can be physical, effecting the body's organ systems (like heart health or reproductive function), or psycho-social (like fear of recurrence), effecting quality of life. We are working to better understand the risk factors for late effects and learn more about how we can help prevent and treat them in the best way possible. Our research efforts have helped us coordinate care with other sub-specialties (or medical teams) for specialized care, develop Survivorship Care Plans to guide the best and safest care after cancer treatment is complete, and it has positioned us to better understand when supportive resources are needed. We continue to learn from our research to better serve our survivors for them to live happy and healthy lives.

If a full article is needed, please email the research team.

Open for enrollment

Title: Effects of Modern Chemotherapy Regimens on Spermatogenesis and Steroidogenesis in Adolescent and Young Adult (AYA) Survivors of Osteosarcoma

Local primary investigator: Rachel Phelan, MD

Purpose: This study is hoping to determine whether infertility and/or biomarkers of spermatogenesis and steroidogenesis differ in male osteosarcoma survivors treated with cisplatin with or without ifosfamide compared to male controls without a history of cancer. This study also hopes to evaluate whether cisplatin with or without ifosfamide for the treatment of osteosarcoma alters sperm DNA methylation.

Quality of life/outcomes

Fertility

Programmatic

Medical - BMT

Medical - Oncology