Monoclonal antibody treatment for COVID-19

Monoclonal antibody treatment for children with certain high risk conditions is available at Children’s Wisconsin. The FDA has approved emergency usage of monoclonal antibodies as a treatment for children with mild to moderate COVID-19 at high risk of progressing to severe disease, plus one or more high risk criteria. This therapy should not be considered as a replacement for COVID-19 vaccination, which is the strongest protection available against the new coronavirus.

At Children’s Wisconsin, we offer a limited number of weekday monoclonal antibody treatment appointments at our Milwaukee hospital campus. Because supply is extremely limited, we are prioritizing children at highest risk of COVID-19.

A child must meet each of the following criteria to be eligible for monoclonal antibody treatment:

  • Be 12 years old or older
  • Weigh at least 88 pounds (40 kilograms)
  • Have mild to moderate COVID-19
  • Have a positive COVID-19 viral test (PCR or antigen)
  • Considered high risk for progressing to severe disease with COVID-19
  • Get treated within 10 days of symptoms starting

High-risk conditions for children include:

  • Immunosuppressive disease or receiving immunosuppressive treatments
  • Diabetes
  • Chronic kidney disease
  • A body mass index (BMI) more than or equal to 35
  • BMI more than or equal to the 85th percentile for age and gender
  • Sickle cell disease
  • Congenital or acquired heart disease
  • Neurodevelopmental disorders
  • Medical-related technological dependence (such as tracheostomy or G-tube)
  • Asthma, reactive airway disease, or other chronic respiratory disease that requires daily medication for control

At this time, not all children who meet criteria and belong to one of the high risk groups will ultimately receive monoclonal antibody therapy due to the need to prioritize the treatment for those with the highest risk. We will continue to partner with our pharmacy for more doses and also look forward to other novel treatments.

If your child is positive for COVID-19 and you think they may qualify, reach out to your primary care or specialty care provider/team.

If your child is scheduled already to receive monoclonal antibodies at Children’s Wisconsin, more information is available.